Automated sub-ppm mass accuracy on an ESI-TOF for use with drug discovery compound libraries
نویسندگان
چکیده
منابع مشابه
Combinatorial compound libraries for drug discovery: an ongoing challenge.
Almost 20 years of combinatorial chemistry have emphasized the power of numbers, a key issue for drug discovery in the current genomic era, in which it has been estimated that there might be more than 10,000 potential targets for which it would be desirable to have small-molecule modulators. Combinatorial chemistry is best described as the industrialization of chemistry; the chemistry has not c...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2007
ISSN: 1044-0305,1879-1123
DOI: 10.1016/j.jasms.2007.06.001